What would 5-HT do? Regional diversity of 5-HT1 receptor modulation of primary afferent neurotransmission
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چکیده
منابع مشابه
Modulation of serotonergic neurotransmission by nitric oxide Running head: NO modulation of 5-HT synapse
Nitric oxide (NO) and serotonin (5-HT) are two neurotransmitters with important roles in neuromodulation and synaptic plasticity. There is substantial evidence for a morphological and functional overlap between these two neurotransmitter systems, in particular the modulation of 5-HT function by nitric oxide. Here we demonstrate for the first time the modulation of an identified serotonergic syn...
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Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT1A autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as anxiety disorders and depression, as well as in the mechanism of antidepressant action. Here, we investigated how persistent alterations in brain 5-H...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2012
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.2012.01963.x